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Author: | T. Mori |
Keywords: | natural pyrethrin, dimefluthrin, non-heating device, metofluthrin |
DOI: | 10.17660/ActaHortic.2017.1169.8 |
Abstract:
Natural pyrethrins have long been used as household insecticides, and d-allethrin and prallethrin, which originate from pyrethrin I, are both used extensively in the control of mosquitoes worldwide.
Modifications in their alcohol moieties have led to the discovery of [2,3,5,6-tetrafluoro-4-(methoxymethyl)phenyl]methyl (1R,3R)-chrysanthemate (dimefluthrin), which has faster knockdown activity than d-allethrin in mosquito coil formulations.
Further modifications to the acid moiety of dimefluthrin revealed that [2,3,5,6-tetrafluoro-4-(methoxymethyl)phenyl]methyl (1R,3R)-norchrysanthemate (metofluthrin) exhibited significant knockdown activity in non-heating devices such as fan vaporizers and paper and resin emanators.
I herein report the discovery of these new pyrethroids and their efficacies against several mosquito species.
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