ISHS Acta Horticulturae 680: III WOCMAP Congress on Medicinal and Aromatic Plants - Volume 6: Traditional Medicine and Nutraceuticals
SEMI-PILOT SCALE PRODUCTION OF PECTIN FROM LIME PEEL WASTE FOR CHOLESTEROL LOWERING AGENT |
| Authors: | P.A. Pirshahid, K. Thisayakorn, R. Giwanon, C. Phoonsiri, T. Kajsongkram, K. Chawananorasest, T. Suntorntanasart, S. Trangwacharakul |
| Keywords: | Citrus aurantifolia, hypolipidemic |
| Abstract:
Pectin was obtained from pilot scale extraction of fresh lime peel wastes [Citrus aurantifolia (Chistm.) Swingle] to yield 12%. Four varieties of lime which are available in Thailand were investigated: Paen Puang, Paen Ramphai, Si Khiew, and Nam Hom Thun Klao. The percent yields of pectin were 12, 11, 11, and 10%, respectively. The purity of four varieties of pectin extracts were investigated by microbial limit tests. The results showed that all extracts conformed to the specification of Thai Herbal Pharmacopoeia. A preliminary study of the effect of TISTR pectin on hypolipidemic in rats induced by Triton WR-1339 (400 mg/kg i.p.) was conducted. The dosages of TISTR pectin in this study were 500, 1,000 and 2,000 mg/kg, and fenofibrate (Lipanthyl 200M) was used as a standard drug. The results showed that it could reduce the serum lipid profiles: cholesterol, triglyceride, HDL and LDL. It also exhibited a dose response activity. | |
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