ISHS Acta Horticulturae 677: III WOCMAP Congress on Medicinal and Aromatic Plants - Volume 3: Perspectives in Natural Product Chemistry
PHYTOCHEMICAL STUDY OF HYMENOCARDIA WALLICHII TUL. |
| Authors: | C. Yenjai, S. Pitchayawasin, S. Bonsupa, S. Sangkul |
| Keywords: | antimycobacterial, friedelin, homopterocarpin, squalene, stigmasterol |
| Abstract:
A primary screening of dichloromethane extract of Hymenocardia wallichii Tul. exhibited activity against Mycobacterium tuberculosis with the minimum inhibitory concentration (MIC) of 100 µg/ml. Chromatographic separation of this extract yielded squalene (1), stigmasterol (2), friedelin (3) and homopterocarpin (4). Squalene possessed antimycobacterial activity with the MIC of 100 µg/ml. This is the first time to report the chemical constituents from this plant. | |
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