ISHS Acta Horticulturae 675: III WOCMAP Congress on Medicinal and Aromatic Plants - Volume 1: Bioprospecting and Ethnopharmacology
PHARMACOGNOSTICAL AND PHYTOCHEMICAL STUDIES ON SOME MEDICINAL PLANTS OF TIRUNEL VELI HILLS IN TAMILNADU IN INDIA |
| Authors: | A.J. De Britto, G.D. Nalini Mable, P. Jeyaraman, A. Saraswathy, P. Brindha |
| Keywords: | aqueous extracts, Breynia retusa, Phyllanthus reticulates, Securinega virosa |
| Abstract:
Aqueous extracts of Securinega virosa, Phyllanthus reticulatus and Breynia retusa were screened for their hepatoprotective properties against carbontetra-chloride induced liver damage in Wistar albino rats. All the extracts gave promising results, thus the plants were taken up for photochemical investigation. Fractionation of the extracts and crystallization of the compounds yielded five compounds that were identified as amyrin, thea alcohol, octacosanol,  -sitosterol and -sitosterol 3- -D glucopyranoside.Among the three plants screened, Seurinega virosa had the best repair mechanism on blood biochemistry, and also correlated with the pathological changes seen in the liver. Histopathological examinations of the liver from the group of rats that received the extract of Securinega virosa revealed almost normal architecture of the liver. | |
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