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ISHS Acta Horticulturae 675: III WOCMAP Congress on Medicinal and Aromatic Plants - Volume 1: Bioprospecting and Ethnopharmacology

CHEMICAL COMPOSITION AND CYTOTOXIC ACTIVITY OF THE ESSENTIAL OIL OF ZINGIBER OTTENSII

Authors:   S. Thubthimthed, P. Limsiriwong, U. Rerk-am, T. Suntorntanasat
Keywords:   humulene, p-cymene, sabinene, terpinen-4-ol, zerumbone, Zingiberaceae
Abstract:
The hydrodistilled essential oil from the rhizome of Zingiber ottensii collected in Phetchaburi province, Thailand was analyzed by GC and GC/MS. Twenty-eight constituents were identified of which zerumbone (40.1%), terpinen-4-ol (11.2%), p-cymene (6.9%), sabinene (6.5%) and humulene (5.6%) were the major components. Cytotoxic activity using brine shrimp lethality test showed moderate toxicity (LC50= 65.5 µg/ml).

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