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ISHS Acta Horticulturae 501: II WOCMAP Congress Medicinal and Aromatic Plants, Part 2: Pharmacognosy, Pharmacology, Phytomedicine, Toxicology

BIOLOGICAL ACTIVITIES IN MEDICINAL SPECIES OF EUPATORIUM

Authors:   M. Clavin, K. Lorenzen, A. Mayer, V. Martino, T. Anke
Keywords:   Eupatorium laevigatum, Eupatorium hecatanthum, Eupatorium candolleanum, Eupatorium macrocephalum, platelet aggregation, cytotoxic, antimicrobial, nematicidal activities
Abstract:
Twenty extracts from four Argentine medicinal Eupatorium species were assayed for cytotoxic, antimicrobial, and nematicidal activities as well as effects on the aggregation of bovine platelets.

Cytotoxic effects and inhibition of platelet aggregation were exhibited by some of the extracts of the four species tested.E. laevigatum showed antifungal activity against Mucor miehei and antibacterial activity against Bacillus brevis in the infusion and dichloromethane extract, respectively. The latter also exhibited significant cytotoxic activity.

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