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ISHS Acta Horticulturae 501: II WOCMAP Congress Medicinal and Aromatic Plants, Part 2: Pharmacognosy, Pharmacology, Phytomedicine, Toxicology

MEDICINAL SPECIES OF THE SOLANACEAE FAMILY : PRIMARY SCREENING OF CYTOTOXICITY

Authors:   E. Mongelli, J. Coussio, G. Ciccia, D. Maestri, J. Zygadlo
Keywords:   antitumoral activity, Argentine plants
Abstract:
Plant species belonging to the Solanaceae family were studied using the Artemia salina bioassay. Ethanolic extracts of Cestrum parqui, Nierembergia aristata, N. hippomanica, N. stricta, Physalis viscosa, Solanum chacoense, S. eleagnifolium, S. glaucophylum, S. incisum, S. stukerti (aerial parts) and Salpichroa origanifolia (fruits and leaves) were analysed. The active plant extracts, the LC50 and the 95 % confidence intervals (μg/mL) obtained were: Nierembergia aristata: 250 (1558–102), N. stricta: 84 (354–380); N. hippomanica: 163 (304–91); Solanum chacoense: 230 (359–154); Salpichroa origanifolia (fruits): 330 (534–203) and S. origanifolia (leaves): 75 (112–49).

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