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ISHS Acta Horticulturae 501: II WOCMAP Congress Medicinal and Aromatic Plants, Part 2: Pharmacognosy, Pharmacology, Phytomedicine, Toxicology

INDOLE ALKALOIDS FROM TABERNAEMONTANA CATHARINENSIS A. DC.

Authors:   P.S. Pereira, D.A. Dias, S.C. França, S.V. Sampaio
Keywords:   Apocynaceae, indole alkaloids, root bark extract
Abstract:
During chemical investigation for compounds possessing biological activity in the root bark of Tabernaemontana catharinensis, six alkaloids were isolated: 12-methoxy-4-methylvoachalotine, coronaridine, coronaridine hydroxyindolenine, voacangine hydroxyindolenine, heyneanine and vobasine. The structures were elucidated by 1H and 13C NMR and the combination of two NMR methods COSY and HMQC.

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