|
|
|
| Authors: | Andrew H. Paterson, T. Lan, Terrye A. Delmonte, S. P. Kowalski |
| Keywords: | QTL, positional cloning, synteny |
Abstract:
Tremendous morphological variation makes Brassica oleracea an important potential model for the isolation of genes important to many aspects of plant growth and development.
The genome size of Brassica, while similar to that of other organisms in which positional cloning has been accomplished, is still large and cumbersome.
In the “plant family tree”, Brassica enjoys a close relationship to the important model Arabidopsis thaliana, with the smallest genome among higher plants.
A significant effort has been made over the past several years to develop detailed comparative maps of Brassica oleracea and Arabidopsis thaliana. By aligning QTLs in Brassica with corresponding chromosomal locations in Arabidopsis, positional cloning of QTLs might be accomplished with remarkable efficacy.
The morphological and DNA polymorphism of Brassica, together with the small genome of Arabidopsis, make the crucifers very important to the next step beyond genome sequencing, the relationship of sequence to function.
Moreover, co-linearity that extends far beyond individual plant families, makes these plants a central tool for gaining better understanding of other genomes.
|
Download Adobe Acrobat Reader (free software to read PDF files) |
|