ISHS Acta Horticulturae 306: International Symposium on Medicinal and Aromatic Plants, XXIII IHC
FAVOURABLE EFFECT OF HIGH DIETARY LEVEL OF GROUND PAPRIKA ON THE CONTRACTILITY AND MEMBRANE STRUCTURE OF MUSCLES IN OLD RATS |
| Authors: | J. Barna, T. Bányász, I. Kalapos, T. Kovács |
| Abstract:
The aim of present experiments was to investigate the slowing-down effect of long term ground paprika feeding on the functional changes in muscles during aging. Adult Wistar male rats were kept for 6 /SP-6 group/ and 12 /SP-12 group/months resp. on a semisynthetic diet containing 35 per cent capsaicine free, ground paprika. Contractile parameters were determined on isolated freshly dissected skeletal muscles (SOL=m. soleus; EDL=m. extensor digitorum longus). The measurements of 3-/H/-ouabain binding were performed by methods of Norgaard et al (1983). The tetanus/twitch ratio of slow SOL muscle from old animals was higher than from young animals. The chronic paprika feeding markedly reduced the tetanus/twitch ratio of SOL and EDL muscles in both /SP-6, SP-12/ groups compared to old controls. A distinct reduction of the optimum frequency in both /slow and fast/ muscles was also caused by the paprika diet. After paprika feeding the density of 3-/H/-ouabain binding sites was increased in EDL muscle, but in SOL muscle the pumping sites density was decreased. Paprika diet caused still the definite reduction of the KD-values /affinity constant/ in EDL and SOL muscles. The chronic paprika feeding altered the contractility and membrane (Na+/K+-ATPase) function of different skeletal muscles in rats. In our opinion the long term paprika feeding causes the rejuvenating effect. | |
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