ISHS Acta Horticulturae 125: Symposium on Chrysanthemum
PREVENTIVE AND CURATIVE ANTICANCER DRUG. APPLICATION TO CROWN-GALL TUMORS |
| Authors: | M. Beljanski, L. Le Goff, A. Faivre-Amiot |
| Abstract:
We describe the in vivo antitumor effect of the compound BG-8 on the induction and/or development of Agrobacterium tumefaciens - induced tumors on pea seedlings and Chrysanthemum plantlets. A single treatment applied before or after bacterial infection leads to a strong tumor-weight decrease without affecting the plant growth. The BG-8 inhibitory effect depends on the duration of treatment and compound concentration. In vitro this substance prevents cancer DNA synthesis and this explains the inhibition of tumor cell multiplication. There is little or no effect on healthy cell DNA in vitro synthesis. | |
Download Adobe Acrobat Reader (free software to read PDF files) | |
